Antiarrhythmic drugs in the management of atrial fibrillation.

نویسنده

  • J C Cowan
چکیده

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Atrial Fibrillation Antiarrhythmic Drug Therapy for Atrial Fibrillation

Antiarrhythmic medications have been available for nearly 100 years and remain a mainstay in the management of atrial fibrillation (AF). Goals of therapy with the use of these drugs include a reduction in the frequency and duration of episodes of arrhythmia as well an emerging goal of reducing mortality and hospitalizations associated with AF. The use of these drugs has been limited by both pro...

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Risk of proarrhythmic events in the Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) study: a multivariate analysis.

OBJECTIVES This study examined the risk of proarrhythmic events in patients receiving antiarrhythmic drugs for treatment of atrial fibrillation (AF) according to present-day safety guidelines. BACKGROUND Advances in understanding the proarrhythmic risk of antiarrhythmic drugs has led to development of safety guidelines for these agents. Such guidelines were used in the Atrial Fibrillation Fol...

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Atrial fibrillation (AF) is a commonly encountered arrhythmia in our daily practice. Every year a huge bulk of data is published about different management strategies, new antiarrhythmic drugs, anticoagulation protocols and ablation procedures in these patients. In this review article, we discuss different management strategies and new antiarrhythmic drugs as well as those commonly used. We wil...

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Atrial fibrillation is the most common arrhythmia encountered in clinical practice and can result in significant morbidity and mortality. Catheter ablation has become a feasible therapeutic option for the management of this complex and challenging arrhythmia. In this article, we have discussed the mechanism of atrial fibrillation, different imaging modalities used for atrial fibrillation ablati...

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Radiofrequency ablation (RFA) for the treatment of paroxysmal Atrial Fibrillation (pAF) has a class 1 indication in patients who have not tolerated or responded to antiarrhythmic medications. Antiarrhythmic medications (AAM) are, however, limited not only by modest efficacy, but also by significant side effects. Discontinuation rates for AAM range from 11-40% in trials. The RAAFT-2 trial evalua...

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عنوان ژورنال:
  • British heart journal

دوره 70 4  شماره 

صفحات  -

تاریخ انتشار 1993